A cervical spacer implant with biobraille with a squared hole, exposing a green laser beam pointed at a surface, creating a symmetrical, black-and-white kaleidoscopic pattern to show biobraille pattern.

BioBraille™

BioBraille™ is the next generation of nanotechnology.

Macro-, micro-, and nanofeatures are “programmed” onto the implant surface utilizing a proprietary and advanced laser etching process. This approach is subtractive (eliminating concerns of possible shearing), highly reproducible, and dimensionally accurate.

BioBraille™ has demonstrated an amplified biologic response in vitro with an abundance of nanofeatures in an advantageous size range to promote cellular attachment and early phase bone production, critical to rapid bone formation and procedural success.

BioBraille™ has earned FDA clearance for the nanotechnology designation

More than meets the eye.

  • Macro Surface

    Mimics trabecular bone structure

    Close-up of a textured surface with an intricate, symmetrical design. biobraille macro pattern SEM

  • Micro Surface

    Provides pits for increased cellular attachment

    A highly magnified microscopic view of a porous surface with numerous holes and complex textured structures, captured at 500x magnification. biobraille micro pattern SEM

  • Nano Surface

    Elicits an endogenous cellular response

    A black and white microscopic image showing protrusions and pits and structures at the nanometer scale. biobraille nano pattern SEM
Laboratory glassware including a test tube, two glass pipettes, and a Petri dish on a light-colored surface.

Pre Clincial Data for BioBraille™

The BioBraille™ surface demonstrated increased, rapid cell attachment when compared to smooth titanium.

Cellular Attachment | Day 14 | ~10x Magnification

A yellow circular spherical object with black branching patterns and dark spots on its surface, resembling a microscopic view cell attachment and proliferation. biobraille.

BioBraille™

A large yellow circular shape with black edges and small black spots. smooth titanium

Smooth Titanium

The BioBraille™ surface has also demonstrated increased expression of Type 1 Collagen, an early marker that is essential for bone formation as the dominant structural protein of bone extracellular matrix (ECM), as well as increased expression of Bone-Sialoprotein and Dentin Matrix Protein, well-established markers of osteogenic differentiation and active bone matrix formation.

4D Projection of Cellular Expression | Day 14

BioBraille™ Surface (Front) | Depth of Proliferation (Side)

Green - Bone Sialoprotein

Red - Dentin Matrix Protein

bone sialoprotein on biobraille surface. cell expression
dentin matrix protein on biobraille surface. cell expression
Line graph showing the expression increase of Type 1 Collagen over time, comparing BioBraille and TCP. The x-axis represents days, and the y-axis shows fold change. BioBraille's fold change peaks at day 15, while TCP's fold change remains relatively steady.
Line graph showing the increase in bone sialoprotein expression over time, with two lines representing BioBraille and TCP; BioBraille's line peaks sharply around day 15 while TCP's line remains relatively flat.

Femtosecond Laser

Femtosecond laser processing is an advancement in technology that allows Spectrum to “program” a macro, micro, and nano surface on selected areas.

  • Subtractive

  • Dimensionally accurate ‍

  • Highly reproducible ‍

Future Innovation Opportunities

Spectrum has enhanced the precision and versatility of nanotechnology integration by enabling targeted application of its proprietary BioBraille™ surface. This approach allows for strategic placement on implant areas requiring immediate bone contact and fusion, while preserving smooth, polished, or articulating surfaces to maintain optimal mobility and performance.

“BioBraille™ represents a transformative evolution in nanotechnology, with broad implications across the orthopedic landscape, including reconstruction, sports medicine, trauma, and dental applications. By combining scientific innovation with clinical insight, Spectrum is helping to redefine standards of care.” - Kelly Shelton, CEO.

Industry titans started it. We refined it – Nano, precisely placed.

A dental implant crown resting on a dental mold of teeth, with a black background.
Line drawing of a human knee joint, showing bones and cartilage.
A grayscale drawing of a hand holding a large sheet of paper or canvas, with a visible sketch or outline of a face on it.
Black and white photo of a human pelvic bone and a part of the thigh bone. An outline of a dog's head is drawn to the left, with dotted lines connecting it to the pelvic bone.
X-ray image of human feet and ankles showing bones against a black background.
X-ray image of a foot, showing bones and fractures.

*All images and technologies shown above are for illustrative purposes only. No device shown is claiming FDA approval or is available for purchase.